Chondroitin sulfate microspheres anchored with drug-loaded liposomes play a dual antioxidant role in the treatment of osteoarthritis

Reactive oxygen species (ROS) play a critical role in the pathogenesis of osteoarthritis. The injection of a single antioxidant drug is characterized by low drug utilization and short residence time in the articular cavity, limiting the therapeutic effect of antioxidant drugs on osteoarthritis. Curr...

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Veröffentlicht in:	Acta biomaterialia 2022-10, Vol.151, p.512-527
Hauptverfasser:	He, Yuzhe, Sun, Miao, Wang, Jirong, Yang, Xiaofu, Lin, Changjian, Ge, Lujie, Ying, Chenting, Xu, Kai, Liu, An, Wu, Lidong
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidation Drug delivery Microsphere Osteoarthritis Reactive oxygen species
Online-Zugang:	Volltext
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