Diagnosis of drug-induced liver injury in model mice by studying the inhibitory effect of serum components on P450 inhibition assay

Drug-induced liver injury (DILI) causes abortive drug development in both clinical and non-clinical phases. Therefore, it is important to develop an evaluation system that can be used to accurately and easily assess DILI during drug development and at an early stage. The diagnosis of diseases using...

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Veröffentlicht in:	Chemico-biological interactions 2022-09, Vol.365, p.110075-110075, Article 110075
Hauptverfasser:	Yonezuka, Yasuhiro, Kuwada, Hiroki, Imaishi, Hiromasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Cytochrome P450 Drug-induced liver injury P450 inhibition assay
Online-Zugang:	Volltext
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