Bilirubin stabilizes the mitochondrial membranes during NLRP3 inflammasome activation

[Display omitted] Mitochondria sense both intracellular and extracellular stress, with the subsequence released mt-ROS resulted from the interruption of its membrane integrity being a direct activator for NLRP3 inflammasome activation. Regulating the morphology and function of mitochondria could be...

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Veröffentlicht in:	Biochemical pharmacology 2022-09, Vol.203, p.115204-115204, Article 115204
Hauptverfasser:	Li, Yufei, Sheng, Hongda, Yan, Ziwei, Guan, Bin, Qiang, Shifa, Qian, Jing, Wang, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Bilirubin High-content imaging analysis Mitochondrial morphofunction NLRP3 inflammasome
Online-Zugang:	Volltext
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