Estrogen receptor variant ER‐α36 facilitates estrogen signaling via EGFR in glioblastoma

Glioblastoma (GBM) is a deadly and common primary brain tumor. Poor prognosis is linked to high proliferation and cell heterogeneity. Sex differences may play a role in patient outcome. Previous studies showed that ER‐α36, a variant of the estrogen receptor (ER), mediated non‐genomic estrogen signal...

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Veröffentlicht in:	Cell biology international 2022-11, Vol.46 (11), p.1759-1774
Hauptverfasser:	Qu, Chao, Wang, Cui, Li, Hongyan, Li, Ying, Han, Chao, Tao, Xiaofeng, Guan, Xin, Zhang, Yejun, Chen, Meng, Liu, Jing, Zou, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain cancer Brain tumors Cell proliferation EGFR Epidermal growth factor Epidermal growth factor receptors ER‐α36 Estrogen receptors Estrogens Genomics Glioblastoma Kinases MAP kinase non‐genomic signaling Patients Phosphorylation Sex differences Src protein Therapeutic targets
Online-Zugang:	Volltext
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