Prevalence of therapeutic drug monitoring and adherence to imatinib in chronic myeloid leukemia in Japan

Objective: The effectiveness of imatinib, a tyrosine kinase inhibitor recommended for the treatment of chronic myeloid leukemia, is associated with high adherence and trough plasma imatinib concentrations of ~ 1,000 ng/mL. However, adherence and therapeutic drug monitoring (TDM) for imatinib have ha...

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Veröffentlicht in:	International journal of clinical pharmacology and therapeutics 2022-11, Vol.60 (11), p.469-476
Hauptverfasser:	Kawabe, Kazuhiro, Nakayama, Toshimitsu, Fukuoka, Noriyasu, Sakamoto, Yasutaka, Goto, Hirohito, Suzuki, Taiichi, Koike, Hirofumi, Sahashi, Yukiko, Ooba, Nobuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Inhibitor drugs Leukemia Targeted cancer therapy Therapeutic drug monitoring
Online-Zugang:	Volltext
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