Regulatory Roles of N- and C-Terminal Cytoplasmic Regions of P4-ATPases

P4-ATPases, which are subfamily members of P-type ATPase superfamily, translocate membrane lipids from the exoplasmic/luminal leaflet to the cytoplasmic leaflet, thus regulating trans-bilayer lipid asymmetry. Mammalian P4-ATPases localize to the specific subcellular organelles or the plasma membrane...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 2022/08/01, Vol.70(8), pp.524-532
Hauptverfasser:	Shin, Hye-Won, Takatsu, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	flippase lipid asymmetry lipid bilayer Lipids Localization Mammalian cells Mammals Membranes Organelles P4-ATPase Regulatory mechanisms (biology) Structural analysis Substrate specificity Substrates
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