Nile tilapia TLR3 recruits MyD88 and TRIF as adaptors and is involved in the NF-κB pathway in the immune response

TLR3 plays a crucial role in innate immunity. In the present study, OnTLR3 was identified in the Nile tilapia Oreochromis niloticus, with a conserved LRR domain and a C-terminal TIR domain. OnTLR3 was broadly expressed in all tissues tested, with the highest expression levels in the blood and the lo...

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Veröffentlicht in:	International journal of biological macromolecules 2022-10, Vol.218, p.878-890
Hauptverfasser:	Gao, Fengying, Pang, Jicai, Lu, Maixin, Liu, Zhigang, Wang, Miao, Ke, Xiaoli, Yi, Mengmeng, Cao, Jianmeng
Format:	Artikel
Sprache:	eng
Schlagworte:	MyD88 and TRIF adaptor Nile tilapia (Oreochromis niloticus) TLR3
Online-Zugang:	Volltext
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