Activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against ceftolozane/tazobactam- and ceftazidime/avibactam-resistant Pseudomonas aeruginosa

Abstract Objectives To evaluate the activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against a clinical and laboratory collection of ceftolozane/tazobactam- and ceftazidime/avibactam-resistant Pseudomonas aeruginosa β-lactamase mutants. Methods The activit...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2022-09, Vol.77 (10), p.2809-2815
Hauptverfasser:	Lasarte-Monterrubio, Cristina, Fraile-Ribot, Pablo Arturo, Vázquez-Ucha, Juan Carlos, Cabot, Gabriel, Guijarro-Sánchez, Paula, Alonso-García, Isaac, Rumbo-Feal, Soraya, Galán-Sánchez, Fátima, Beceiro, Alejandro, Arca-Suárez, Jorge, Oliver, Antonio, Bou, Germán
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Azabicyclo Compounds - pharmacology Azabicyclo Compounds - therapeutic use beta-Lactamases - genetics Borinic Acids Carboxylic Acids Cefepime - pharmacology Cefepime - therapeutic use Cefiderocol Ceftazidime - pharmacology Ceftazidime - therapeutic use Cephalosporins - pharmacology Cephalosporins - therapeutic use Cyclooctanes Humans Imipenem - pharmacology Imipenem - therapeutic use Piperidines Pseudomonas aeruginosa - genetics Pseudomonas Infections - drug therapy Tazobactam - pharmacology Tazobactam - therapeutic use
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