Characterization of Astrocytes in the Minocycline-Administered Mouse Photothrombotic Ischemic Stroke Model

Astrocytes, together with microglia, play important roles in the non-infectious inflammation and scar formation at the brain infarct during ischemic stroke. After ischemia occurs, these become highly reactive, accumulate at the infarction, and release various inflammatory signaling molecules. The re...

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Veröffentlicht in:	Neurochemical research 2022-09, Vol.47 (9), p.2839-2855
Hauptverfasser:	Kondo, Mari, Okazaki, Haruka, Nakayama, Kei, Hohjoh, Hirofumi, Nakagawa, Kimie, Segi-Nishida, Eri, Hasegawa, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Apoptosis Astrocytes Biochemistry Biomedical and Life Sciences Biomedicine Brain research Cell Biology Cerebral infarction Cytokines Fatty acid-binding protein Fatty acids Gene expression Growth factors Infarction Inflammation Ischemia Laboratories Localization Microglia Minocycline mRNA Necrosis Neurochemistry Neurology Neurosciences Original Paper Pharmaceuticals Phenotypes Proteins Science Stroke Tumor necrosis factor-α Tumors
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