Androgen receptor mutations for precision medicine in prostate cancer

Hormonal therapies including androgen deprivation therapy and androgen receptor (AR) pathway inhibitors such as abiraterone and enzalutamide have been widely used to treat advanced prostate cancer. However, treatment resistance emerges after hormonal manipulation in most prostate cancers, and it is...

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Veröffentlicht in:	Endocrine-related cancer 2022-10, Vol.29 (10), p.R143-R155
Hauptverfasser:	Shiota, Masaki, Akamatsu, Shusuke, Tsukahara, Shigehiro, Nagakawa, Shohei, Matsumoto, Takashi, Eto, Masatoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptors Androgens Antiandrogens Biopsy Mutation Mutation hot spots Precision medicine Prostate cancer Review Steroid hormones Tumors
Online-Zugang:	Volltext
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