Acetylation of p62 regulates base excision repair through interaction with APE1

p62, a well-known adaptor of autophagy, plays multiple functions in response to various stresses. Here, we report a function for p62 in base excision repair that is distinct from its known functions. Loss of p62 impairs base excision repair capacity and increases the sensitivity of cancer cells to a...

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Veröffentlicht in:	Cell reports (Cambridge) 2022-07, Vol.40 (3), p.111116-111116, Article 111116
Hauptverfasser:	Li, Meiting, Xiong, Jiannan, Yang, Liqian, Huang, Jie, Zhang, Yu, Liu, Minghui, Wang, Lina, Ji, Jianguo, Zhao, Ying, Zhu, Wei-Guo, Luo, Jianyuan, Wang, Haiying
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylation APE1 base excision repair hMOF p62 SIRT7
Online-Zugang:	Volltext
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