N-acetyl-L-cysteine ameliorates hepatocyte pyroptosis of dog type 1 diabetes mellitus via suppression of NLRP3/NF-κB pathway

Type 1 diabetes mellitus (T1DM) is a chronic and represented by insulin-causing pancreatic β-cell disruption and hyperglycemia. N-Acetyl-Cysteine (NAC) is regarded as facilitating endothelial cell function and angiogenesis and may have treatment effect in the case of diabetes. However, the impact of...

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Veröffentlicht in:	Life sciences (1973) 2022-10, Vol.306, p.120802-120802, Article 120802
Hauptverfasser:	Huo, Haihua, Wu, Haitong, Ma, Feiyang, Li, Xinrun, Liao, Jianzhao, Hu, Lianmei, Han, Qingyue, Li, Ying, Pan, Jiaqiang, Zhang, Hui, Tang, Zhaoxin, Guo, Jianying
Format:	Artikel
Sprache:	eng
Schlagworte:	Diabetes mellitus Dog Insulin NAC Pyroptosis
Online-Zugang:	Volltext
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