Is Tranexamic Acid Beneficial in Open Spine Surgery ? and its Effects Vary by Dosage, Age, Sites, and Locations: A Meta-Analysis of Randomized Controlled Trials

The role of tranexamic acid (TXA) in controlling blood loss during spine surgery remains unclear. With the publication of new randomized controlled trials (RCTs), we conducted a meta-analysis to determine the safety and efficacy of TXA in spine surgery. PubMed, Embase, Web of Science, and Cochrane d...

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Veröffentlicht in:	World neurosurgery 2022-10, Vol.166, p.141-152
Hauptverfasser:	Liu, Zhen-Gang, Yang, Fan, Zhu, Yu-Hang, Liu, Guang-Chen, Zhu, Qing-San, Zhang, Bo-Yin
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifibrinolytic Agents - therapeutic use Blood loss Blood Loss, Surgical - prevention & control Humans Meta-analysis Randomized controlled trial Randomized Controlled Trials as Topic Spinal Dysraphism Spine surgery Tranexamic acid Tranexamic Acid - therapeutic use
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