PIK3CB promotes oesophageal cancer proliferation through the PI3K/AKT/mTOR signalling axis

PIK3CB is abnormally expressed in various carcinomas and affects the proliferation, invasion and drug resistance of cancer cells. However, its role in oesophageal squamous cell carcinoma (ESCC) is still unclear. In this study, PIK3CB was found to be highly expressed in ESCC tissues and cells and pos...

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Veröffentlicht in:	Cell biology international 2022-09, Vol.46 (9), p.1399-1408
Hauptverfasser:	Xu, Wei, Wang, Zhiqiang, Zhang, Zhi, Xu, Jian, Jiang, Yuequan
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT AKT protein Apoptosis Cell cycle Cell proliferation Drug resistance ESCC Esophageal cancer hypomethylation PIK3CB Signal transduction Squamous cell carcinoma TOR protein Tumors
Online-Zugang:	Volltext
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