S100A4-dependent glycolysis promotes lymphatic vessel sprouting in tumor

Tumor-induced lymphangiogenesis promotes the formation of new lymphatic vessels, contributing to lymph nodes (LNs) metastasis of tumor cells in both mice and humans. Vessel sprouting appears to be a critical step in this process. However, how lymphatic vessels sprout during tumor lymphangiogenesis i...

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Veröffentlicht in:	Angiogenesis (London) 2023-02, Vol.26 (1), p.19-36
Hauptverfasser:	Li, Anqi, Zhu, Linyu, Lei, Ningjing, Wan, Jiajia, Duan, Xixi, Liu, Shuangqing, Cheng, Yanru, Wang, Ming, Gu, Zhuoyu, Zhang, Huilei, Bai, Yueyue, Zhang, Li, Wang, Fazhan, Ni, Chen, Qin, Zhihai
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cancer Research Cardiology Cell Biology Endothelial cells Endothelial Cells - metabolism Glycolysis Humans Hypoxia Lymph nodes Lymphangiogenesis - physiology Lymphatic Metastasis - pathology Lymphatic system Lymphatic Vessels - metabolism Metastases Metastasis Mice Oncology Ophthalmology Original Paper S100 Calcium-Binding Protein A4 - genetics S100 Calcium-Binding Protein A4 - metabolism S100A4 protein Tumor cells Tumors Vessels
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