Tirzepatide: First Approval

Tirzepatide (Mounjaro™) is a single molecule that combines dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. Native GIP and GLP-1 are incretin hormones that stimulate insulin secretion and decrease glucagon secretion. GIP also plays a r...

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Bibliographische Detailangaben
Veröffentlicht in:	Drugs (New York, N.Y.) N.Y.), 2022-07, Vol.82 (11), p.1213-1220
1. Verfasser:	Syed, Yahiya Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	AdisInsight Report Adults Antidiabetics Apnea Appetite Congestive heart failure Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Disorders Energy metabolism Gastric emptying GIP protein Glucagon Glucagon-like peptide 1 Glucose Heart failure Hormones Insulin Insulin resistance Insulin secretion Internal Medicine Medicine Medicine & Public Health Metabolism Metabolites Morbidity Obesity Pharmacokinetics Pharmacology/Toxicology Pharmacotherapy Plasma Polypeptides Satiety Secretion Sleep apnea Sleep disorders
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