Aspartic Acid-Modified Phospholipids Regulate Cell Response and Rescue Memory Deficits in APP/PS1 Transgenic Mice

Misfolding and accumulation of amyloid-β (Aβ) to form senile plaques are the main neuropathological signatures of Alzheimer’s disease (AD). Decreasing Aβ production, inhibiting Aβ aggregation, and clearing Aβ plaques are thus considered an important strategy for AD treatment. However, numerous drugs...

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Veröffentlicht in:ACS chemical neuroscience 2022-07, Vol.13 (14), p.2154-2163
Hauptverfasser: Wang, Xue, Gao, Huiling, Zhang, Xiaoyu, Qian, Shengxu, Wang, Cunli, Deng, Lijing, Zhong, Manli, Qing, Guangyan
Format: Artikel
Sprache:eng
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