Upregulation of MHC-I and downregulation of PD-L1 expression by doxorubicin and deferasirox codelivered liposomal nanoparticles for chemoimmunotherapy of melanoma

[Display omitted] Tumor immunotherapy is a promising strategy to activate the immune system and eliminate tumors. Major histocompatibility complex I (MHC-I) is usually applied to potentiate antigen presentation, but it is associated with upregulation of programmed death ligand 1 (PD-L1) expression,...

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Veröffentlicht in:	International journal of pharmaceutics 2022-08, Vol.624, p.122002-122002, Article 122002
Hauptverfasser:	Song, Panpan, Han, Xiaoqing, Zheng, Runxiao, Yan, Jiao, Wu, Xiaqing, Wang, Yanjing, Zhang, Haiyuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemoimmunotherapy DFX DOX MHC-I PD-L1 pH-Sensitive liposome
Online-Zugang:	Volltext
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