Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis

First-line treatments for mild to moderate psoriasis are typically topical formulations containing corticosteroids, however, the therapeutic efficacy of these formulations is compromised by limited penetration and skin retention. Even more challenging, off-target corticosteroids are known to adverse...

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Veröffentlicht in:	Journal of controlled release 2022-09, Vol.349, p.354-366
Hauptverfasser:	Mai, Yang, Ouyang, Yaqi, Yu, Mian, Qin, Yujia, Girardi, Michael, Saltzman, W. Mark, Cocco, Emiliano, Zhao, Chao, Yu, Liu, Jia, Yizhen, Xiao, Lingyun, Dou, Liu, Deng, Wenbin, Liu, Yang, Xie, Julin, Deng, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Disease-specific treatment Formulation optimization Local drug delivery Psoriasis Single-dose cure Surface-modified nanoparticles
Online-Zugang:	Volltext
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