The pharmacokinetics and pharmacodynamics of dexamethasone following epidural SP-102 or intravenous dexamethasone sodium phosphate injection in subjects with lumbosacral radicular pain

Objectives: To evaluate the pharmacokinetics, pharmacodynamics (PD), safety, and tolerability of epidural SP-102 (10 mg dexamethasone sodium phosphate injectable gel) compared to an intravenous injection of 10 mg dexamethasone sodium phosphate, USP (IV USP). Materials and methods: Subjects with lumb...

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Veröffentlicht in:	International journal of clinical pharmacology and therapeutics 2022-09, Vol.60 (9), p.408-416
Hauptverfasser:	Yee, Shiyin, Robson, Richard, Stannard, Elizabeth, Lal, Ritu, Lissin, Dmitri
Format:	Artikel
Sprache:	eng
Schlagworte:	Epidural Pharmacodynamics Pharmacokinetics Steroids
Online-Zugang:	Volltext
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