An Experimental Dermal Oedema Model for Apx Toxins of Actinobacillus pleuropneumoniae

In-vivo models of Actinobacillus pleuropneumoniae (App) infection in pigs are required for the development of vaccines and investigations of pathogenicity. Existing models cause severe respiratory disease with pulmonary oedema, dyspnoea and severe thoracic pain, and careful monitoring and early inte...

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Veröffentlicht in:	Journal of comparative pathology 2022-07, Vol.195, p.12-18
Hauptverfasser:	Soutter, Francesca, Priestnall, Simon L., Catchpole, Brian, Rycroft, Andrew N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinobacillus pleuropneumoniae animal model edema euthanasia histopathology inflammation pain pathogenicity respiratory tract diseases serotypes skin subcutaneous injection toxin
Online-Zugang:	Volltext
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