Cognitive decline in mid-life: Changes in memory and cognition related to hypothyroidism

This study assessed specific cognitive impairments within a primarily female, hypothyroid population, while controlling for factors that commonly contribute to cognitive decline. Participants (N = 739) included 461 individuals with hypothyroidism. This study involved an online survey assessing sever...

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Veröffentlicht in:Journal of health psychology 2023-03, Vol.28 (4), p.388-401
Hauptverfasser: Stern, Mark, Finch, Alyse, Haskard-Zolnierek, Kelly B., Howard, Krista, Deason, Rebecca G.
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container_end_page 401
container_issue 4
container_start_page 388
container_title Journal of health psychology
container_volume 28
creator Stern, Mark
Finch, Alyse
Haskard-Zolnierek, Kelly B.
Howard, Krista
Deason, Rebecca G.
description This study assessed specific cognitive impairments within a primarily female, hypothyroid population, while controlling for factors that commonly contribute to cognitive decline. Participants (N = 739) included 461 individuals with hypothyroidism. This study involved an online survey assessing several aspects of memory and cognition. Those with hypothyroidism generally scored worse on self-assessments of memory, higher perceived stress, high rates of depression and anxiety, greater fatigue, poorer concentration, and less motivation. A Receiver Operating Characteristic curve indicated that the cognitive questionnaires are successful at classifying hypothyroidism and a mediation analysis showed fatigue is a mediating symptom of these cognitive outcomes.
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subjects Anxiety
Cognition
Cognitive Dysfunction - etiology
Cognitive impairment
Depression
Fatigue
Fatigue - psychology
Female
Humans
Hypothyroidism
Hypothyroidism - complications
Hypothyroidism - psychology
Memory
Motivation
title Cognitive decline in mid-life: Changes in memory and cognition related to hypothyroidism
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