Antibacterial and antibiotic modifying activity of chalcone (2E)-1-(4′-aminophenyl)-3-(4-methoxyphenyl)-prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps: In vitro and in silico approaches

A large number of infections are caused by multi-resistant bacteria worldwide, increasing to around 700,000 deaths per year. Because of that, many strategies are being developed to combat the resistance of microorganisms to drugs, and recently, chalcones have been studied for this purpose. Chalcones...

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Veröffentlicht in:	Microbial pathogenesis 2022-08, Vol.169, p.105664-105664, Article 105664
Hauptverfasser:	Silva, Jacilene, Esmeraldo Rocha, Janaína, da Cunha Xavier, Jayze, Sampaio de Freitas, Thiago, Douglas Melo Coutinho, Henrique, Nogueira Bandeira, Paulo, Rodrigues de Oliveira, Mateus, Nunes da Rocha, Matheus, Machado Marinho, Emanuelle, de Kassio Vieira Monteiro, Norberto, Ribeiro, Lyanna Rodrigues, Róseo Paula Pessoa Bezerra de Menezes, Ramon, Machado Marinho, Márcia, Magno Rodrigues Teixeira, Alexandre, Silva dos Santos, Hélcio, Silva Marinho, Emmanuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Chalcone Efflux pump Infections MepA NorA Staphylococcus aureus
Online-Zugang:	Volltext
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