Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium

Surveillance pouchoscopy is recommended for patients with restorative proctocolectomy with ileal pouch–anal anastomosis in ulcerative colitis or familial adenomatous polyposis, with the surveillance interval depending on the risk of neoplasia. Neoplasia in patients with ileal pouches mainly have a g...

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Veröffentlicht in:The lancet. Gastroenterology & hepatology 2022-09, Vol.7 (9), p.871-893
Hauptverfasser: Kiran, Ravi P, Kochhar, Gursimran S, Kariv, Revital, Rex, Douglas K, Sugita, Akira, Rubin, David T, Navaneethan, Udayakumar, Hull, Tracy L, Ko, Huaibin Mabel, Liu, Xiuli, Kachnic, Lisa A, Strong, Scott, Iacucci, Marietta, Bemelman, Willem, Fleshner, Philip, Safyan, Rachael A, Kotze, Paulo G, D'Hoore, André, Faiz, Omar, Lo, Simon, Ashburn, Jean H, Spinelli, Antonino, Bernstein, Charles N, Kane, Sunanda V, Cross, Raymond K, Schairer, Jason, McCormick, James T, Farraye, Francis A, Chang, Shannon, Scherl, Ellen J, Schwartz, David A, Bruining, David H, Philpott, Jessica, Bentley-Hibbert, Stuart, Tarabar, Dino, El-Hachem, Sandra, Sandborn, William J, Silverberg, Mark S, Pardi, Darrell S, Church, James M, Shen, Bo
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container_end_page 893
container_issue 9
container_start_page 871
container_title The lancet. Gastroenterology & hepatology
container_volume 7
creator Kiran, Ravi P
Kochhar, Gursimran S
Kariv, Revital
Rex, Douglas K
Sugita, Akira
Rubin, David T
Navaneethan, Udayakumar
Hull, Tracy L
Ko, Huaibin Mabel
Liu, Xiuli
Kachnic, Lisa A
Strong, Scott
Iacucci, Marietta
Bemelman, Willem
Fleshner, Philip
Safyan, Rachael A
Kotze, Paulo G
D'Hoore, André
Faiz, Omar
Lo, Simon
Ashburn, Jean H
Spinelli, Antonino
Bernstein, Charles N
Kane, Sunanda V
Cross, Raymond K
Schairer, Jason
McCormick, James T
Farraye, Francis A
Chang, Shannon
Scherl, Ellen J
Schwartz, David A
Bruining, David H
Philpott, Jessica
Bentley-Hibbert, Stuart
Tarabar, Dino
El-Hachem, Sandra
Sandborn, William J
Silverberg, Mark S
Pardi, Darrell S
Church, James M
Shen, Bo
description Surveillance pouchoscopy is recommended for patients with restorative proctocolectomy with ileal pouch–anal anastomosis in ulcerative colitis or familial adenomatous polyposis, with the surveillance interval depending on the risk of neoplasia. Neoplasia in patients with ileal pouches mainly have a glandular source and less often are of squamous cell origin. Various grades of neoplasia can occur in the prepouch ileum, pouch body, rectal cuff, anal transition zone, anus, or perianal skin. The main treatment modalities are endoscopic polypectomy, endoscopic ablation, endoscopic mucosal resection, endoscopic submucosal dissection, surgical local excision, surgical circumferential resection and re-anastomosis, and pouch excision. The choice of the treatment modality is determined by the grade, location, size, and features of neoplastic lesions, along with patients' risk of neoplasia and comorbidities, and local endoscopic and surgical expertise.
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title Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium
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