Comparison of Restenosis Risk in Single-Layer versus Dual-Layer Carotid Stents: A Duplex Ultrasound Evaluation

Purpose The aim of this study was to report intermediate-term results of duplex ultrasound follow-up of carotid artery stenting performed with the dual-layer stent as compared to concurrent patients treated with other commercially available single-layer carotid stents. Materials and Methods A single...

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Veröffentlicht in:Cardiovascular and interventional radiology 2022-09, Vol.45 (9), p.1257-1266
Hauptverfasser: Sýkora, Ján, Zeleňák, Kamil, Vorčák, Martin, Števík, Martin, Sýkorová, Martina, Sivák, Jozef, Rovňák, Marek, Zapletalová, Jana, Mužík, Juraj, Šinák, Igor, Kurča, Egon, Meyer, Lukas, Fiehler, Jens
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Sprache:eng
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Zusammenfassung:Purpose The aim of this study was to report intermediate-term results of duplex ultrasound follow-up of carotid artery stenting performed with the dual-layer stent as compared to concurrent patients treated with other commercially available single-layer carotid stents. Materials and Methods A single centre, retrospective, nonrandomized study including 162 non-consecutive patients with 199 implanted carotid stents treated over a 7-year period was conducted. Patients with at least one ultrasound examination after treatment were included. Procedural and follow-up data for patients treated with the dual-layer stent implantation (83 stents) vs first-generation carotid stents implantations (116 stents) were compared. Results The median follow-up time was 24.0 months (IQR 10–32 months) for dual-layer stents and 27.5 months (IQR 10.3–59 months) for single-layer stents. The rate of severe restenosis was significantly higher in the dual-layer stent group than in the single-layer group (13.3% [11/83] vs 3.4% [4/116], p  = 0.01). Seven reinterventions were performed in 5 patients with dual-layer stents. The rate of reintervention was significantly higher compared to no reinterventions in single-layer stents (6% [5/83] vs 0% [0/116], p  = 0.012). Patients with restenosis had significantly higher presence of dyslipidaemia (100% [12/12] vs 63.3% [95/150], p  = 0.009). Conclusions In this real-world cohort of patients undergoing carotid artery stenting, the patients treated with low-profile dual-layer micromesh stent showed higher rates of restenosis and reinterventions compared to first-generation single-layer stents.
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-022-03200-4