Oncogenic gain of function due to p53 amyloids occurs through aberrant alteration of cell cycle and proliferation

Transcription factor p53 (also known as TP53) has been shown to aggregate into cytoplasmic and nuclear inclusions, compromising its native tumor suppressive functions. Recently, p53 has been shown to form amyloids, which play a role in conferring cancerous properties to cells, leading to tumorigenes...

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Veröffentlicht in:	Journal of cell science 2022-08, Vol.135 (15)
Hauptverfasser:	Navalkar, Ambuja, Paul, Ajoy, Sakunthala, Arunima, Pandey, Satyaprakash, Dey, Amit Kumar, Saha, Sandhini, Sahoo, Sarthak, Jolly, Mohit Kumar, Maiti, Tushar K., Maji, Samir K.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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