Zinc acetate-promoted blocking of the ATRA process with alkyl halides enabling photochemical alkylamination of olefins

Organic photoredox-catalyzed alkylamination of olefins is performed with alkyl halides and nitrile solvent by blocking the traditional photoredox-ATRA process with Zn(OAc) 2 . A range of carbon-centered radicals (α-alkylcarbonyl, benzyl, cyanomethyl) are effectively participating in this strategy giving rise to versatile carboamination products with high synthetic value. Introducing Zn(OAc) 2 as a blocker in the traditional photo-redox ATRA process, enabling alkylamination of olefins with alkylhalides and nitrile solvent.