Sildenafil attenuates intestinal injury in necrotizing enterocolitis independently of endothelial nitric oxide synthase

•Necrotizing enterocolitis is a devastating disease that afflicts premature infants and for which targeted treatment options are lacking.•Sildenafil improves clinical outcomes and protects the intestine when administered orally in a murine model of necrotizing enterocolitis. This protection is provi...

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Veröffentlicht in:	Journal of pediatric surgery 2022-12, Vol.57 (12), p.967-973
Hauptverfasser:	Hunter, Chelsea E., Hosfield, Brian D., Mesfin, Fikir M., Pecoraro, Anthony R., Liu, Jianyun, Shelley, W. Christopher, Manohar, Krishna, Markel, Troy A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Endothelial nitric oxide synthase ENOS NEC Necrotizing enterocolitis Sildenafil
Online-Zugang:	Volltext
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