TLR4 in Tph2 neurons modulates anxiety-related behaviors in a sex-dependent manner

TLR4 belongs to the TLR receptor family and can induce a proinflammatory response to invading pathogens. Recent studies have identified that TLR4 is associated with major anxiety disorder. Tph2 is a rate-limiting enzyme for 5-HT biosynthesis that is expressed at high levels in the DRN, which include...

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Veröffentlicht in:	Neuropharmacology 2022-09, Vol.216, p.109175-109175, Article 109175
Hauptverfasser:	Li, Yongxiang, Zhu, Shuqing, Xie, Kailai, Feng, Xiajie, Chen, Lvshuang, Wu, Xin, Sun, Zhonghua, Shu, Gang, Wang, Songbo, Zhu, Canjun, Gao, Ping, Jiang, Qingyan, Wang, Lina
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT Anxiety TLR4 Tph2 neurons
Online-Zugang:	Volltext
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