Application of the Functionality Transfer Oligodeoxynucleotide for the Site-Selective Modification of RNA with a Divers Molecule

Due to the importance of the RNA chemical modifications, methods for the selective chemical modification at a predetermined site of the internal position of RNA have attracted much attention. We have developed functional artificial nucleic acids that modify a specific site of RNA in a site- and base...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 2022/07/01, Vol.70(7), pp.498-504
Hauptverfasser:	Togo, Norihiro, Murase, Hirotaka, Lee, Jeongsu, Taniguchi, Yosuke, Sasaki, Shigeki
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes Chemical modification copper-catalyzed azide-alkyne cycloaddition Cycloaddition Cytosine functionality transfer Nucleic acids oligodeoxynucleotide Oligonucleotides Polyethylene glycol Pyridines Ribonucleic acid RNA RNA modification Thioguanine
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