Establishing the relationship between familial dysbetalipoproteinemia and genetic variants in the APOE gene

Familial Dysbetalipoproteinemia (FD) is the second most common monogenic dyslipidemia and is associated with a very high cardiovascular risk due to cholesterol‐enriched remnant lipoproteins. FD is usually caused by a recessively inherited variant in the APOE gene (ε2ε2), but variants with dominant i...

Ausführliche Beschreibung