Effect of metformin on arginine and dimethylarginines in patients with advanced type 2 diabetes: A post hoc analysis of a randomized trial

Aim To study the effect of metformin on plasma levels of arginine, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA), indicators of the nitric oxide pathway. Materials and Methods In this post hoc analysis of the HOME trial, we analysed plasma levels of arginine, ADMA and SDMA...

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Veröffentlicht in:	Diabetes, obesity & metabolism obesity & metabolism, 2022-10, Vol.24 (10), p.1983-1988
Hauptverfasser:	Top, Wiebe M. C., Lehert, Philippe, Schalkwijk, Casper G., Stehouwer, Coen D. A., Kooy, Adriaan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidiabetics Arginine cardiovascular disease Diabetes Diabetes mellitus (non-insulin dependent) Insulin Metformin Nitric oxide Placebos Plasma Plasma levels randomized trial Statistical analysis type 2 diabetes
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