Imaging of Transmembrane AMPA Receptor Regulatory Proteins by Positron Emission Tomography

The transmembrane α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid (AMPA) receptor regulatory protein γ-8 (TARP γ-8) constitutes an auxiliary subunit of AMPA receptors, which mediates various brain functions including learning and memory. TARP γ-8 has emerged as a promising therapeutic target f...

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Veröffentlicht in:	Journal of medicinal chemistry 2022-07, Vol.65 (13), p.9144-9158
Hauptverfasser:	Yu, Qingzhen, Kumata, Katsushi, Rong, Jian, Chen, Zhen, Yamasaki, Tomoteru, Chen, Jiahui, Xiao, Zhiwei, Ishii, Hideki, Hiraishi, Atsuto, Shao, Tuo, Zhang, Yiding, Hu, Kuan, Xie, Lin, Fujinaga, Masayuki, Zhao, Chunyu, Mori, Wakana, Collier, Thomas, Haider, Achi, Tomita, Susumu, Zhang, Ming-Rong, Liang, Steven
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - diagnostic imaging Brain - metabolism Calcium Channels - metabolism Hippocampus - metabolism Mammals - metabolism Positron-Emission Tomography Receptors, AMPA - metabolism
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