The EEF1AKMT3/MAP2K7/TP53 axis suppresses tumor invasiveness and metastasis in gastric cancer

The importance of methylation in the tumorigenic responses of nonhistone proteins, such as TP53, PTEN, RB1, AKT, and STAT3, has been emphasized in numerous studies. In parallel, the corresponding nonhistone protein methyltransferases have been acknowledged in the pathophysiology of cancer. Thus, thi...

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Veröffentlicht in:	Cancer letters 2022-09, Vol.544, p.215803-215803, Article 215803
Hauptverfasser:	Hong, Yo Han, Aziz, Nur, Park, Jae Gwang, Lee, Dagyeong, Kim, Jin Kyeong, Kim, Seung A., Choi, Wooram, Lee, Chae Young, Lee, Hwa Pyoung, Huyen Trang, Ha Thi, Kim, Han Gyung, Jeon, Young-Jun, Kim, Bokyoung, Kim, Younghoon, Kim, Kyung-Hee, Yoo, Byong Chul, Han, Jeung-Whan, Parameswaran, Narayana, Kim, Ji Hye, Hur, Hoon, Cho, Jae Youl
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Antibodies Cell culture Cloning EEF1AKMT3 Gastric cancer Gastric tumor Gene expression Invasiveness MAP2K7 Mass spectroscopy Medical prognosis Medical research Metastases Metastasis Methylation Methyltransferase Mutagenesis Nonhistone proteins p53 Protein Phosphorylation Pore size Protein methylation Proteins PTEN protein Software Stat3 protein TP53 Tumor suppressor Tumorigenesis Tumors Ubiquitination
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