Thyroid hormone resistance: Mechanisms and therapeutic development

As an essential primary hormone, thyroid hormone (TH) is indispensable for human growth, development and metabolism. Impairment of TH function in several aspects, including TH synthesis, activation, transportation and receptor-dependent transactivation, can eventually lead to thyroid hormone resista...

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Veröffentlicht in:	Molecular and cellular endocrinology 2022-08, Vol.553, p.111679-111679, Article 111679
Hauptverfasser:	Yao, Benqiang, Yang, Chunyan, Pan, Chengxi, Li, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Molecular mechanism Receptor mutations Structure-activity relationship Therapeutic development Thyroid hormone receptor Thyroid hormone resistance
Online-Zugang:	Volltext
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