Vaccine-Strain Varicella Virus Transmitted to a Term Infant Following Maternal Postpartum Vaccination

Vaccine-Strain Varicella Virus Transmitted to a Term Infant Following Maternal Postpartum Vaccination

Varicella is a highly contagious disease caused by Varicella-zoster virus (VZV). The American College of Obstetricians and Gynecologists (ACOG) adopted the routine administration of varicella vaccine to varicella non-immune mothers postpartum before leaving the facility per the Advisory Committee in...

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Veröffentlicht in:Journal of the Pediatric Infectious Diseases Society 2022-10, Vol.11 (10), p.452-453
Hauptverfasser: Saringkarisate, Kornkanok, Len, Kyra A, Melish, Marian E, Prothero, Bryscen K, Ching, Natascha
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container_issue 10
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container_title Journal of the Pediatric Infectious Diseases Society
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creator Saringkarisate, Kornkanok
Len, Kyra A
Melish, Marian E
Prothero, Bryscen K
Ching, Natascha
description Varicella is a highly contagious disease caused by Varicella-zoster virus (VZV). The American College of Obstetricians and Gynecologists (ACOG) adopted the routine administration of varicella vaccine to varicella non-immune mothers postpartum before leaving the facility per the Advisory Committee in Immunization Practices (ACIP) recommendation of Varicella prevention. While the vaccine is well-tolerated, a live attenuated vaccine has the potential to cause clinical symptoms and complications, including rash. Secondary transmission of the vaccine virus from healthy persons is rare. Only 13 confirmed cases of secondary transmission from 11 immunocompetent vaccine recipients have been reported. We report the confirmed case of extensive neonatal varicella disease in a neonate after exposure to a vaccine varicella rash that developed after maternal postpartum vaccination.
doi_str_mv 10.1093/jpids/piac050
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title Vaccine-Strain Varicella Virus Transmitted to a Term Infant Following Maternal Postpartum Vaccination
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