A Hemagglutinin 1 Carrying Plant-Based Virus-like Particle Vaccine Generates an Efficacious Cellular Response by Exploiting IL-1 Signaling in Both Adult and Aged Mice

Inactivated influenza vaccines have struggled to provide consistent protection in older individuals. Circumventing immune senescence, an aging of the immune response characterized by weak humoral responses to vaccines, and unchecked inflammation during infection require novel immunization strategies...

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Veröffentlicht in:ImmunoHorizons 2022-06, Vol.6 (6), p.384-397
Hauptverfasser: Alvarez, Fernando, Istomine, Roman, Hendin, Hilary, Hodgins, Breanna, Pillet, Stephane, Fritz, Jörg H., Charland, Nathalie, Ward, Brian J., Piccirillo, Ciriaco A.
Format: Artikel
Sprache:eng
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