Histidine auxotroph mutant is defective for cell separation and allows the identification of crucial factors for cell division in Brucella abortus

The pathogenic bacterium Brucella abortus invades and multiplies inside host cells. To grow inside host cells, B. abortus requires a functional histidine biosynthesis pathway. Here, we show that a B. abortus histidine auxotroph mutant also displays an unexpected chaining phenotype. The intensity of...

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Veröffentlicht in:	Molecular microbiology 2022-09, Vol.118 (3), p.145-154
Hauptverfasser:	Roba, Agnès, Carlier, Elodie, Godessart, Pierre, Naili, Cerine, De Bolle, Xavier
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Biosynthesis Brucella Brucella abortus Cell culture Cell division Chaining Elk Genetic suppression Genotype & phenotype Histidine Mutants peptidoglycan Peptidoglycans Phenotypes
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