Polystyrene microplastics-induced cardiotoxicity in chickens via the ROS-driven NF-κB-NLRP3-GSDMD and AMPK-PGC-1α axes

Microplastics (MPs) pollution is getting increasingly prominent, and its dangers have attracted widespread attention. The heart is the central hub of the organism's survival, and the mechanism of MPs-induced heart injury in chickens is unknown. Here, we investigated the effects of 5 μm polystyr...

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Veröffentlicht in:	The Science of the total environment 2022-09, Vol.840, p.156727-156727, Article 156727
Hauptverfasser:	Zhang, Yue, Yin, Kai, Wang, Dongxu, Wang, Yu, Lu, Hongmin, Zhao, Hongjing, Xing, Mingwei
Format:	Artikel
Sprache:	eng
Schlagworte:	AMPK-PGC-1α pathway Cardiotoxicity Chickens Microplastic NF-κB-NLRP3-GSDMD axis Reactive oxygen species
Online-Zugang:	Volltext
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