Phillygenin ameliorates nonalcoholic fatty liver disease via TFEB-mediated lysosome biogenesis and lipophagy

Lipophagy is an autophagic process, which delivers the intracellular lipid droplets to the lysosomes for degradation. Recent studies revealed that the impairment of lysosomal biogenesis and autophagic flux led to dysregulation of lipophagy in hepatocytes, which exacerbated the development of nonalco...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2022-08, Vol.103, p.154235-154235, Article 154235
Hauptverfasser:	Zhou, Wenling, Yan, Xu, Zhai, Yuanyuan, Liu, Hao, Guan, Lingling, Qiao, Yuan, Jiang, Jizhi, Peng, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagic flux Lipophagy NAFLD Phillygenin TFEB
Online-Zugang:	Volltext
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