Attenuated T cell activation and rearrangement of T cell receptor β repertoire in silica nanoparticle-induced pulmonary fibrosis of mice

Silica nanoparticles (SiNPs) cause pulmonary fibrosis through a complex immune response, but the underlying mechanisms by which SiNPs interact with T cells and affect their functions remain unclear. The T cell receptor (TCR) repertoire is closely related to T cell activation and proliferation and me...

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Veröffentlicht in:	Environmental research 2022-10, Vol.213, p.113678-113678, Article 113678
Hauptverfasser:	Bao, Lei, Geng, Zihan, Wang, Juan, He, Liyi, Kang, Aijuan, Song, Jianshi, Huang, Xiaoyan, Zhang, Yaling, Liu, Qingping, Jiang, Tao, Pang, Yaxian, Niu, Yujie, Zhang, Rong
Format:	Artikel
Sprache:	eng
Schlagworte:	Pulmonary fibrosis Silica nanoparticle T cell activation TCR repertoire
Online-Zugang:	Volltext
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