Neoadjuvant Trastuzumab and Pyrotinib for Locally Advanced HER2-Positive Breast Cancer (NeoATP): Primary Analysis of a Phase II Study

PURPOSEDespite accumulating evidence on dual blockade of HER2 for locally advanced HER2-positive breast cancer, no robust evidence supports the addition of pyrotinib to trastuzumab in the neoadjuvant setting. The NeoATP trial aimed to evaluate the efficacy and safety of pyrotinib with neoadjuvant tr...

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Veröffentlicht in:Clinical cancer research 2022-09, Vol.28 (17), p.3677-3685
Hauptverfasser: Yin, Wenjin, Wang, Yaohui, Wu, Ziping, Ye, Yumei, Zhou, Liheng, Xu, Shuguang, Lin, Yanping, Du, Yueyao, Yan, Tingting, Yang, Fan, Zhang, Jie, Liu, Qiang, Lu, Jinsong
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Sprache:eng
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