Glycan expression profile of signet ring cell gastric cancer cells and potential applicability of rBC2LCN-targeted lectin drug conjugate therapy

Background Signet ring cell carcinoma (SRC) is a distinct subtype of gastric cancer (GC); however, the specific characteristics of cancer cell surface glycans and glycosylation remain unclear. In this study, we investigated SRC-specific glycans using lectin microarray and evaluated the potential app...

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Veröffentlicht in:Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2022-09, Vol.25 (5), p.896-905
Hauptverfasser: Yang, Yu, Akashi, Yoshimasa, Shimomura, Osamu, Tateno, Hiroaki, Saito, Sayoko, Hiemori, Keiko, Miyazaki, Yoshihiro, Furuta, Tomoaki, Kitaguchi, Daichi, Kuroda, Yukihito, Pakavarin, Louphrasitthiphol, Oda, Tatsuya
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Sprache:eng
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