Tumors derived from lung cancer cells respond differently to treatment with sodium valproate (a HDAC inhibitor) in a chicken embryo chorioallantoic membrane model

Lung cancer is the most frequent cause of cancer death. Some human lung malignant tumors have a combined small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) histology, with tumor cell phenotype changing during tumor progression. Valproic acid is used as an anti-seizure medication to...

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Veröffentlicht in:	Histology and histopathology 2022-12, Vol.37 (12), p.1201-1212
Hauptverfasser:	Diržiuvienė, Raminta, Šlekienė, Lina, Palubinskienė, Jolita, Balnytė, Ingrida, Lasienė, Kristina, Stakišaitis, Donatas, Valančiūtė, Angelija
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinoma, Non-Small-Cell Lung - pathology Cell Line, Tumor Chick Embryo Chickens Chorioallantoic Membrane - pathology Histone Deacetylase Inhibitors - pharmacology Humans Lung - metabolism Lung Neoplasms - metabolism Small Cell Lung Carcinoma - metabolism Valproic Acid - pharmacology
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