Adaptive immune resistance at the tumour site: mechanisms and therapeutic opportunities

Tumours employ various tactics to adapt and eventually resist immune attack. These mechanisms are collectively called adaptive immune resistance (AIR). The first defined and therapeutically validated AIR mechanism is the selective induction of programmed cell death 1 ligand 1 (PDL1) by interferon-γ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature reviews. Drug discovery 2022-07, Vol.21 (7), p.529-540
Hauptverfasser:	Kim, Tae Kon, Vandsemb, Esten N., Herbst, Roy S., Chen, Lieping
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67 692/308/153 692/699/67/1059/2325 Antibodies Antigens Apoptosis Biomedical and Life Sciences Biomedicine Biotechnology Cancer Research Clinical trials Drug development Immunotherapy Ligands Lung cancer Lymphocytes Medical research Medicinal Chemistry Melanoma Molecular Medicine Perspective Pharmacology/Toxicology Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!