MiR-106b-5p Attenuates Neuropathic Pain by Regulating the P2X4 Receptor in the Spinal Cord in Mice

The P2X4 receptor (P2X4R) can be upregulated after nerve injury, and its mediated spinal microglial activation makes a critical contribution to pathologically enhanced pain processing in the dorsal horn. Although some studies have partly clarified the mechanism underlying altered P2X4R expression, t...

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Veröffentlicht in:	Journal of molecular neuroscience 2022-08, Vol.72 (8), p.1764-1778
Hauptverfasser:	Du, Huiying, Wu, Danlei, Zhong, Shuotao, Wei, Xuhong, Yuan, Zhongmin, Gong, Qingjuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Biomedical and Life Sciences Biomedicine Cell Biology Dorsal horn Fluorescence Fluorescence in situ hybridization Gene expression Lipopolysaccharides Localization MicroRNAs miRNA Nerves Neuralgia Neurochemistry Neurology Neurosciences Pain Pathogenesis Proteomics Receptors Spinal cord Transfection
Online-Zugang:	Volltext
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