Anterolateral ligament of the knee—Cadaver study in a Caucasian population

Despite the recognized importance of the anterolateral ligament (ALL) in rotational stability of the knee, some studies still deny its role and even its existence. We studied the prevalence of the ALL in a Caucasian population, as well as its characteristics and anatomical relationships. The study w...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Revista española de cirugía ortopédica y traumatología 2023-03, Vol.67 (2), p.134-138
Hauptverfasser: Fernandes, J.C., Pinho, A.R., Pereira, P.A., Madeira, M.D., Raposo, F.A., Sousa, A.N., Lobo, J.M.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 138
container_issue 2
container_start_page 134
container_title Revista española de cirugía ortopédica y traumatología
container_volume 67
creator Fernandes, J.C.
Pinho, A.R.
Pereira, P.A.
Madeira, M.D.
Raposo, F.A.
Sousa, A.N.
Lobo, J.M.
description Despite the recognized importance of the anterolateral ligament (ALL) in rotational stability of the knee, some studies still deny its role and even its existence. We studied the prevalence of the ALL in a Caucasian population, as well as its characteristics and anatomical relationships. The study was performed on 20 knees from 10 embalmed cadavers. A lateral approach, as described by Steven Claes, was used and the relations of the ALL with the lateral epicondyle, lateral inferior genicular artery, lateral meniscus, Gerdy's tubercle and fibular head were recorded. Its length and its width were also measured. The ALL was identified in 16 knees. Its origin was at a distance inferior to 1mm posterior and proximal to the lateral femoral epicondyle and insertion within a mean distance of 2.1±0.6mm from de tibial articular surface, 20.6±1.3mm from the Gerdy's tubercle and 20.3±1.2mm from the fibular head. In all cases ALL presented mutual fibers with the lateral meniscus. The length was 35.8±4.6mm and the width was 4.2±1.3/4.9±1.0/6.5±1.5mm at its proximal, middle and distal third, respectively. No difference was found between gender and the dimensions of the ligament. The ALL was found in 80% of the knees. Its origin is closely related to the lateral collateral ligament and its insertion is halfway between the fibular head and the Gerdy's tubercle. In all cases, we verified the connection between ALL and the lateral meniscus. Aunque ha sido reconocida la importancia del ligamento anterolateral (ALL) en la estabilidad rotacional de la rodilla, algunos estudios siguen negando su existencia. Estudiamos la prevalencia del ALL en una población caucásica, así como sus características y relaciones anatómicas. El estudio se realizó en 20 rodillas de 10 cadáveres embalsamados. Se utilizó un abordaje lateral, como lo describe Steven Claes, y se registraron las relaciones del ALL con el epicóndilo lateral, la arteria genicular inferior lateral, el menisco lateral, el tubérculo de Gerdy y la cabeza del peroné. También se midió el ancho y el largo. El ALL fue identificado en 16 rodillas. Su origen estaba a una distancia inferior a 1mm posterior y proximal al epicóndilo femoral lateral y su inserción a una distancia media de 2,1±0,6mm de la superficie articular tibial, 20,6±1,3mm de la tuberosidad de Gerdy y 20,3±1,2mm de la cabeza del peroné. En todos los casos se presentaban fibras mutuas con el menisco lateral. El largo fue de 35,8±4,6mm y el ancho fue de 4,2±1,3/4,9±1,0/
doi_str_mv 10.1016/j.recot.2022.06.001
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2675986903</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1888441522001497</els_id><sourcerecordid>2675986903</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1991-b23d70549c057fdb894f158d71cc58cc19d35ba74715710756b9dedb469429773</originalsourceid><addsrcrecordid>eNp9kDtOxDAQhi0EYnmdAAm5pNlgJ_GroEArXtJKNFBbjj0BL9l4sRMkOg7BCTkJhl0oaWam-P4Z-0PomJKCEsrPFkUEG4aiJGVZEF4QQrfQHlVSTqVkfDvPMs91TdkE7ae0IITXVNFdNKkYV5QJsYfmF_0AMXQmV9Phzj-aJfQDDi0engA_9wCf7x8z48wrRJyG0b1h32ODZ2a0JnnT41VYjTnvQ3-IdlrTJTja9AP0cHV5P7uZzu-ub2cX86mlStFpU1ZOEFYrS5hoXSNV3VImnaDWMmkz5CrWGFGL_EZKBOONcuCamqu6VEJUB-h0vXcVw8sIadBLnyx0nekhjEmXXDAluSJVRqs1amNIKUKrV9EvTXzTlOhvjXqhfzTqb42acJ015tTJ5sDYLMH9ZX69ZeB8DUD-5quHqJP10FtwPm8btAv-3wNfrBaEvw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2675986903</pqid></control><display><type>article</type><title>Anterolateral ligament of the knee—Cadaver study in a Caucasian population</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elsevier ScienceDirect Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Fernandes, J.C. ; Pinho, A.R. ; Pereira, P.A. ; Madeira, M.D. ; Raposo, F.A. ; Sousa, A.N. ; Lobo, J.M.</creator><creatorcontrib>Fernandes, J.C. ; Pinho, A.R. ; Pereira, P.A. ; Madeira, M.D. ; Raposo, F.A. ; Sousa, A.N. ; Lobo, J.M.</creatorcontrib><description>Despite the recognized importance of the anterolateral ligament (ALL) in rotational stability of the knee, some studies still deny its role and even its existence. We studied the prevalence of the ALL in a Caucasian population, as well as its characteristics and anatomical relationships. The study was performed on 20 knees from 10 embalmed cadavers. A lateral approach, as described by Steven Claes, was used and the relations of the ALL with the lateral epicondyle, lateral inferior genicular artery, lateral meniscus, Gerdy's tubercle and fibular head were recorded. Its length and its width were also measured. The ALL was identified in 16 knees. Its origin was at a distance inferior to 1mm posterior and proximal to the lateral femoral epicondyle and insertion within a mean distance of 2.1±0.6mm from de tibial articular surface, 20.6±1.3mm from the Gerdy's tubercle and 20.3±1.2mm from the fibular head. In all cases ALL presented mutual fibers with the lateral meniscus. The length was 35.8±4.6mm and the width was 4.2±1.3/4.9±1.0/6.5±1.5mm at its proximal, middle and distal third, respectively. No difference was found between gender and the dimensions of the ligament. The ALL was found in 80% of the knees. Its origin is closely related to the lateral collateral ligament and its insertion is halfway between the fibular head and the Gerdy's tubercle. In all cases, we verified the connection between ALL and the lateral meniscus. Aunque ha sido reconocida la importancia del ligamento anterolateral (ALL) en la estabilidad rotacional de la rodilla, algunos estudios siguen negando su existencia. Estudiamos la prevalencia del ALL en una población caucásica, así como sus características y relaciones anatómicas. El estudio se realizó en 20 rodillas de 10 cadáveres embalsamados. Se utilizó un abordaje lateral, como lo describe Steven Claes, y se registraron las relaciones del ALL con el epicóndilo lateral, la arteria genicular inferior lateral, el menisco lateral, el tubérculo de Gerdy y la cabeza del peroné. También se midió el ancho y el largo. El ALL fue identificado en 16 rodillas. Su origen estaba a una distancia inferior a 1mm posterior y proximal al epicóndilo femoral lateral y su inserción a una distancia media de 2,1±0,6mm de la superficie articular tibial, 20,6±1,3mm de la tuberosidad de Gerdy y 20,3±1,2mm de la cabeza del peroné. En todos los casos se presentaban fibras mutuas con el menisco lateral. El largo fue de 35,8±4,6mm y el ancho fue de 4,2±1,3/4,9±1,0/6,5±1,5mm en su tercio proximal, medio y distal. El ALL se encontró en el 80% de las rodillas. Su origen está íntimamente relacionado con el ligamento colateral lateral y su inserción se encuentra a media distancia entre la cabeza del peroné y el tubérculo de Gerdy. En todos los casos comprobamos la conexión entre el ALL y el menisco lateral.</description><identifier>ISSN: 1888-4415</identifier><identifier>EISSN: 1988-8856</identifier><identifier>DOI: 10.1016/j.recot.2022.06.001</identifier><identifier>PMID: 35691577</identifier><language>eng</language><publisher>Spain: Elsevier España, S.L.U</publisher><subject>Anterior Cruciate Ligament ; Anterolateral ; Cadaver ; Cadáver ; Disección ; Dissection ; Humans ; Knee ; Knee Joint ; Ligaments, Articular ; Menisci, Tibial ; Rodilla ; Tibia</subject><ispartof>Revista española de cirugía ortopédica y traumatología, 2023-03, Vol.67 (2), p.134-138</ispartof><rights>2022</rights><rights>Copyright © 2022. Publicado por Elsevier España, S.L.U.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1991-b23d70549c057fdb894f158d71cc58cc19d35ba74715710756b9dedb469429773</cites><orcidid>0000-0003-1158-9730 ; 0000-0003-1277-0638 ; 0000-0002-6017-4390 ; 0000-0003-2298-3143 ; 0000-0002-7085-6926</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1888441522001497$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,860,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35691577$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fernandes, J.C.</creatorcontrib><creatorcontrib>Pinho, A.R.</creatorcontrib><creatorcontrib>Pereira, P.A.</creatorcontrib><creatorcontrib>Madeira, M.D.</creatorcontrib><creatorcontrib>Raposo, F.A.</creatorcontrib><creatorcontrib>Sousa, A.N.</creatorcontrib><creatorcontrib>Lobo, J.M.</creatorcontrib><title>Anterolateral ligament of the knee—Cadaver study in a Caucasian population</title><title>Revista española de cirugía ortopédica y traumatología</title><addtitle>Rev Esp Cir Ortop Traumatol</addtitle><description>Despite the recognized importance of the anterolateral ligament (ALL) in rotational stability of the knee, some studies still deny its role and even its existence. We studied the prevalence of the ALL in a Caucasian population, as well as its characteristics and anatomical relationships. The study was performed on 20 knees from 10 embalmed cadavers. A lateral approach, as described by Steven Claes, was used and the relations of the ALL with the lateral epicondyle, lateral inferior genicular artery, lateral meniscus, Gerdy's tubercle and fibular head were recorded. Its length and its width were also measured. The ALL was identified in 16 knees. Its origin was at a distance inferior to 1mm posterior and proximal to the lateral femoral epicondyle and insertion within a mean distance of 2.1±0.6mm from de tibial articular surface, 20.6±1.3mm from the Gerdy's tubercle and 20.3±1.2mm from the fibular head. In all cases ALL presented mutual fibers with the lateral meniscus. The length was 35.8±4.6mm and the width was 4.2±1.3/4.9±1.0/6.5±1.5mm at its proximal, middle and distal third, respectively. No difference was found between gender and the dimensions of the ligament. The ALL was found in 80% of the knees. Its origin is closely related to the lateral collateral ligament and its insertion is halfway between the fibular head and the Gerdy's tubercle. In all cases, we verified the connection between ALL and the lateral meniscus. Aunque ha sido reconocida la importancia del ligamento anterolateral (ALL) en la estabilidad rotacional de la rodilla, algunos estudios siguen negando su existencia. Estudiamos la prevalencia del ALL en una población caucásica, así como sus características y relaciones anatómicas. El estudio se realizó en 20 rodillas de 10 cadáveres embalsamados. Se utilizó un abordaje lateral, como lo describe Steven Claes, y se registraron las relaciones del ALL con el epicóndilo lateral, la arteria genicular inferior lateral, el menisco lateral, el tubérculo de Gerdy y la cabeza del peroné. También se midió el ancho y el largo. El ALL fue identificado en 16 rodillas. Su origen estaba a una distancia inferior a 1mm posterior y proximal al epicóndilo femoral lateral y su inserción a una distancia media de 2,1±0,6mm de la superficie articular tibial, 20,6±1,3mm de la tuberosidad de Gerdy y 20,3±1,2mm de la cabeza del peroné. En todos los casos se presentaban fibras mutuas con el menisco lateral. El largo fue de 35,8±4,6mm y el ancho fue de 4,2±1,3/4,9±1,0/6,5±1,5mm en su tercio proximal, medio y distal. El ALL se encontró en el 80% de las rodillas. Su origen está íntimamente relacionado con el ligamento colateral lateral y su inserción se encuentra a media distancia entre la cabeza del peroné y el tubérculo de Gerdy. En todos los casos comprobamos la conexión entre el ALL y el menisco lateral.</description><subject>Anterior Cruciate Ligament</subject><subject>Anterolateral</subject><subject>Cadaver</subject><subject>Cadáver</subject><subject>Disección</subject><subject>Dissection</subject><subject>Humans</subject><subject>Knee</subject><subject>Knee Joint</subject><subject>Ligaments, Articular</subject><subject>Menisci, Tibial</subject><subject>Rodilla</subject><subject>Tibia</subject><issn>1888-4415</issn><issn>1988-8856</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDtOxDAQhi0EYnmdAAm5pNlgJ_GroEArXtJKNFBbjj0BL9l4sRMkOg7BCTkJhl0oaWam-P4Z-0PomJKCEsrPFkUEG4aiJGVZEF4QQrfQHlVSTqVkfDvPMs91TdkE7ae0IITXVNFdNKkYV5QJsYfmF_0AMXQmV9Phzj-aJfQDDi0engA_9wCf7x8z48wrRJyG0b1h32ODZ2a0JnnT41VYjTnvQ3-IdlrTJTja9AP0cHV5P7uZzu-ub2cX86mlStFpU1ZOEFYrS5hoXSNV3VImnaDWMmkz5CrWGFGL_EZKBOONcuCamqu6VEJUB-h0vXcVw8sIadBLnyx0nekhjEmXXDAluSJVRqs1amNIKUKrV9EvTXzTlOhvjXqhfzTqb42acJ015tTJ5sDYLMH9ZX69ZeB8DUD-5quHqJP10FtwPm8btAv-3wNfrBaEvw</recordid><startdate>202303</startdate><enddate>202303</enddate><creator>Fernandes, J.C.</creator><creator>Pinho, A.R.</creator><creator>Pereira, P.A.</creator><creator>Madeira, M.D.</creator><creator>Raposo, F.A.</creator><creator>Sousa, A.N.</creator><creator>Lobo, J.M.</creator><general>Elsevier España, S.L.U</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-1158-9730</orcidid><orcidid>https://orcid.org/0000-0003-1277-0638</orcidid><orcidid>https://orcid.org/0000-0002-6017-4390</orcidid><orcidid>https://orcid.org/0000-0003-2298-3143</orcidid><orcidid>https://orcid.org/0000-0002-7085-6926</orcidid></search><sort><creationdate>202303</creationdate><title>Anterolateral ligament of the knee—Cadaver study in a Caucasian population</title><author>Fernandes, J.C. ; Pinho, A.R. ; Pereira, P.A. ; Madeira, M.D. ; Raposo, F.A. ; Sousa, A.N. ; Lobo, J.M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1991-b23d70549c057fdb894f158d71cc58cc19d35ba74715710756b9dedb469429773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Anterior Cruciate Ligament</topic><topic>Anterolateral</topic><topic>Cadaver</topic><topic>Cadáver</topic><topic>Disección</topic><topic>Dissection</topic><topic>Humans</topic><topic>Knee</topic><topic>Knee Joint</topic><topic>Ligaments, Articular</topic><topic>Menisci, Tibial</topic><topic>Rodilla</topic><topic>Tibia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fernandes, J.C.</creatorcontrib><creatorcontrib>Pinho, A.R.</creatorcontrib><creatorcontrib>Pereira, P.A.</creatorcontrib><creatorcontrib>Madeira, M.D.</creatorcontrib><creatorcontrib>Raposo, F.A.</creatorcontrib><creatorcontrib>Sousa, A.N.</creatorcontrib><creatorcontrib>Lobo, J.M.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Revista española de cirugía ortopédica y traumatología</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fernandes, J.C.</au><au>Pinho, A.R.</au><au>Pereira, P.A.</au><au>Madeira, M.D.</au><au>Raposo, F.A.</au><au>Sousa, A.N.</au><au>Lobo, J.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anterolateral ligament of the knee—Cadaver study in a Caucasian population</atitle><jtitle>Revista española de cirugía ortopédica y traumatología</jtitle><addtitle>Rev Esp Cir Ortop Traumatol</addtitle><date>2023-03</date><risdate>2023</risdate><volume>67</volume><issue>2</issue><spage>134</spage><epage>138</epage><pages>134-138</pages><issn>1888-4415</issn><eissn>1988-8856</eissn><abstract>Despite the recognized importance of the anterolateral ligament (ALL) in rotational stability of the knee, some studies still deny its role and even its existence. We studied the prevalence of the ALL in a Caucasian population, as well as its characteristics and anatomical relationships. The study was performed on 20 knees from 10 embalmed cadavers. A lateral approach, as described by Steven Claes, was used and the relations of the ALL with the lateral epicondyle, lateral inferior genicular artery, lateral meniscus, Gerdy's tubercle and fibular head were recorded. Its length and its width were also measured. The ALL was identified in 16 knees. Its origin was at a distance inferior to 1mm posterior and proximal to the lateral femoral epicondyle and insertion within a mean distance of 2.1±0.6mm from de tibial articular surface, 20.6±1.3mm from the Gerdy's tubercle and 20.3±1.2mm from the fibular head. In all cases ALL presented mutual fibers with the lateral meniscus. The length was 35.8±4.6mm and the width was 4.2±1.3/4.9±1.0/6.5±1.5mm at its proximal, middle and distal third, respectively. No difference was found between gender and the dimensions of the ligament. The ALL was found in 80% of the knees. Its origin is closely related to the lateral collateral ligament and its insertion is halfway between the fibular head and the Gerdy's tubercle. In all cases, we verified the connection between ALL and the lateral meniscus. Aunque ha sido reconocida la importancia del ligamento anterolateral (ALL) en la estabilidad rotacional de la rodilla, algunos estudios siguen negando su existencia. Estudiamos la prevalencia del ALL en una población caucásica, así como sus características y relaciones anatómicas. El estudio se realizó en 20 rodillas de 10 cadáveres embalsamados. Se utilizó un abordaje lateral, como lo describe Steven Claes, y se registraron las relaciones del ALL con el epicóndilo lateral, la arteria genicular inferior lateral, el menisco lateral, el tubérculo de Gerdy y la cabeza del peroné. También se midió el ancho y el largo. El ALL fue identificado en 16 rodillas. Su origen estaba a una distancia inferior a 1mm posterior y proximal al epicóndilo femoral lateral y su inserción a una distancia media de 2,1±0,6mm de la superficie articular tibial, 20,6±1,3mm de la tuberosidad de Gerdy y 20,3±1,2mm de la cabeza del peroné. En todos los casos se presentaban fibras mutuas con el menisco lateral. El largo fue de 35,8±4,6mm y el ancho fue de 4,2±1,3/4,9±1,0/6,5±1,5mm en su tercio proximal, medio y distal. El ALL se encontró en el 80% de las rodillas. Su origen está íntimamente relacionado con el ligamento colateral lateral y su inserción se encuentra a media distancia entre la cabeza del peroné y el tubérculo de Gerdy. En todos los casos comprobamos la conexión entre el ALL y el menisco lateral.</abstract><cop>Spain</cop><pub>Elsevier España, S.L.U</pub><pmid>35691577</pmid><doi>10.1016/j.recot.2022.06.001</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-1158-9730</orcidid><orcidid>https://orcid.org/0000-0003-1277-0638</orcidid><orcidid>https://orcid.org/0000-0002-6017-4390</orcidid><orcidid>https://orcid.org/0000-0003-2298-3143</orcidid><orcidid>https://orcid.org/0000-0002-7085-6926</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1888-4415
ispartof Revista española de cirugía ortopédica y traumatología, 2023-03, Vol.67 (2), p.134-138
issn 1888-4415
1988-8856
language eng
recordid cdi_proquest_miscellaneous_2675986903
source MEDLINE; DOAJ Directory of Open Access Journals; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals
subjects Anterior Cruciate Ligament
Anterolateral
Cadaver
Cadáver
Disección
Dissection
Humans
Knee
Knee Joint
Ligaments, Articular
Menisci, Tibial
Rodilla
Tibia
title Anterolateral ligament of the knee—Cadaver study in a Caucasian population
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T17%3A09%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Anterolateral%20ligament%20of%20the%20knee%E2%80%94Cadaver%20study%20in%20a%20Caucasian%20population&rft.jtitle=Revista%20espa%C3%B1ola%20de%20cirug%C3%ADa%20ortop%C3%A9dica%20y%20traumatolog%C3%ADa&rft.au=Fernandes,%20J.C.&rft.date=2023-03&rft.volume=67&rft.issue=2&rft.spage=134&rft.epage=138&rft.pages=134-138&rft.issn=1888-4415&rft.eissn=1988-8856&rft_id=info:doi/10.1016/j.recot.2022.06.001&rft_dat=%3Cproquest_cross%3E2675986903%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2675986903&rft_id=info:pmid/35691577&rft_els_id=S1888441522001497&rfr_iscdi=true