Fungal Patterns Induce Cytokine Expression through Fluxes of Metabolic Intermediates That Support Glycolysis and Oxidative Phosphorylation

Cytokine expression is fine-tuned by metabolic intermediates, which makes research on immunometabolism suitable to yield drugs with a wider prospect of application than the biological therapies that block proinflammatory cytokines. Switch from oxidative phosphorylation (OXPHOS) to glycolysis has bee...

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Veröffentlicht in:The Journal of immunology (1950) 2022-06, Vol.208 (12), p.2779-2794
Hauptverfasser: Mancebo, Cristina, Fernández, José Javier, Herrero-Sánchez, Carmen, Alvarez, Yolanda, Alonso, Sara, Sandoval, Tito A, Cubillos-Ruiz, Juan R, Montero, Olimpio, Fernández, Nieves, Crespo, Mariano Sánchez
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Sprache:eng
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