Myeloid immune checkpoint ILT3/LILRB4/gp49B can co-tether fibronectin with integrin on macrophages

Abstract LILRB4 (B4, also known as ILT3/CD85k) is an immune checkpoint of myeloid lineage cells, albeit its mode of function remains obscure. Our recent identification of a common ligand for both human B4 and its murine ortholog gp49B as the fibronectin (FN) N-terminal 30 kDa domain poses the questi...

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Veröffentlicht in:International immunology 2022-07, Vol.34 (8), p.435-444
Hauptverfasser: Itoi, So, Takahashi, Naoyuki, Saito, Haruka, Miyata, Yusuke, Su, Mei-Tzu, Kezuka, Dai, Itagaki, Fumika, Endo, Shota, Fujii, Hiroshi, Harigae, Hideo, Sakamoto, Yuzuru, Takai, Toshiyuki
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Sprache:eng
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