Nickel-Catalyzed Chemo- and Regioselective Arylcyanation of β,γ-Unsaturated Amides

A nickel-catalyzed intermolecular arylcyanation of 8-aminoquinolinyl β,γ-unsaturated amides is reported. The three-component reaction directly afforded diverse β-cyano γ-aryl amides with exclusive chemo- and regioselectivity. The synthetic practicality of this approach is further demonstrated throug...

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Veröffentlicht in:Organic letters 2022-06, Vol.24 (24), p.4328-4332
Hauptverfasser: Hu, Jinghui, Du, Qiang, Zhao, Yao, Zhang, Fei, Chen, Rizhi, Zhou, Jianrong Steve, Wu, Xiaojin
Format: Artikel
Sprache:eng
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